Upbit, South Korea's largest cryptocurrency exchange, has announced the listing of Bio Protocol (BIO) trading pairs against KRW, BTC, and USDT. The trading is scheduled to commence on October 20, 2025, at 18:00 KST. This significant development is poised to impact the decentralized science (DeSci) sector and highlights Upbit's influence in global cryptocurrency markets.
The listing process involves initial trade limitations, a standard procedure implemented by Upbit to manage potential volatility and ensure market stability, thereby protecting investors.
Market Reaction and DeSci Sector Impact
Following the announcement of the listing, BIO experienced a substantial price increase, with gains ranging between 40% and 58%. This surge reflects significant investor enthusiasm and has heightened interest in the DeSci sector and other related decentralized science tokens.
Financially, BIO's market capitalization saw a 40% increase, propelling it into the top 200 cryptocurrencies by market value. Concurrently, the broader DeSci token category witnessed double-digit gains, with Upbit's spotlight further amplifying the sector's potential.
Broader Sector Performance and Expert Commentary
The decentralized science sector as a whole experienced an appreciation of 11.5%, indicating a positive market sentiment and a recognition of the financial potential within these emerging technologies.
Historical data suggests that Upbit listings frequently result in sharp increases in both price and trading volume, underscoring the crucial role major exchanges play in token valuation. Market observers note that these patterns are influential in shaping overall market dynamics.
Simon Dedic, Investor and Crypto KOL, commented on the situation: "Everyone knows what an Upbit listing can do by now. But have you ever seen a single Upbit listing send an entire category? Just when you think DeSci is dead, BIO comes out and single-handedly runs it back."

