Bio Protocol's BIO token is now live for trading on BNB Chain. Users can swap BIO on PancakeSwap and interact with the project’s decentralized science (DeSci) tools directly through BNB's infrastructure. This expansion broadens Bio Protocol’s presence across major ecosystems and integrates its scientific research platform with one of the largest smart-contract networks. The launch also introduces new pathways for BioAgents, tokenized research workflows, and upcoming products in decentralized science.
DeSci is coming to @BNBCHAIN 🧪$BIO is now tradable on BNB, with more DeSci tokens coming.
— Bio Protocol (@BioProtocol) December 2, 2025
This paves the way for Bio's Launchpad & x402-enabled BioAgents on BNB.
Details👇 pic.twitter.com/fs9CFEmK3u
What Is Bio Protocol and Why Does the BIO Token Matter?
Bio Protocol is a decentralized science platform that unites biotechnology, artificial intelligence, and blockchain within a unified research system. The BIO token facilitates onchain coordination, provides access to AI models, supports staking tools, and enables scientific workflows that operate across multiple networks. The new BNB Chain version of BIO maintains the same contract logic as the original asset, and additional Bio tokens are expected to be bridged over in the coming weeks.
Bio Protocol has shared the BNB contract address:
0x226a2fa2556c48245e57cd1cba4c6c9e67077dd2
This launch grants BNB Chain users direct access to Bio’s scientific infrastructure, including DeSci staking, the Bio Launchpad, and systems designed to support AI-native experimentation.
Background: Funding and Expansion Into Full-Stack DeSci
This listing follows Bio Protocol's successful fundraising round, where it secured $6.9 million in a round anchored by Maelstrom Fund. Other notable participants included Mechanism Capital, Animoca Brands, Presto Labs, and several biotech investors. The raised capital is being allocated to the development of a full-stack platform that integrates AI tools, scientific communities, decentralized funding mechanisms, and drug discovery pipelines.
Traditional research environments often suffer from slow and fragmented coordination. While AI laboratories at institutions like Google DeepMind, Stanford, and major pharmaceutical companies utilize advanced tools, these are frequently confined within internal systems. Bio Protocol offers an alternative, providing a pathway for independent researchers, smaller laboratories, patients, and crypto users to collaborate with shared AI models and maintain verifiable research records onchain.
Paul Kohlhaas, Founder and CEO of Bio Protocol, has stated that science often operates within "institutional black boxes." The project aims to empower researchers and communities with direct control over data, funding, and attribution through its blockchain infrastructure.
What Are BioAgents and How Do They Work?
BioAgents are autonomous AI models designed to function as "co-scientists" within the Bio ecosystem. Each agent possesses the capability to generate hypotheses, manage digital wallets, secure funding for experiments, and coordinate tasks with full onchain transparency.
Key capabilities include:
- •Continuous Funding
Each BioAgent operates with its own onchain wallet, enabling it to receive funds and allocate them to research laboratories. This mechanism bypasses the protracted grant approval processes that frequently impede early-stage research. - •Crowdsourced Learning
Agents acquire knowledge by analyzing encrypted data vaults, communication channels, and community contributions. This information is used to update a unified knowledge graph that supports scientific reasoning. - •Onchain Recordkeeping
All actions performed by BioAgents are recorded onchain, establishing verifiable trails for attribution and mitigating the risk of lost work or uncredited contributions. - •Monetization of Knowledge
Agents generate revenue through collaborations with pharmaceutical clients, consumer-facing tools, or markets linked to scientific discoveries. Funds are then distributed to contributors based on transparent onchain rules.
The inaugural BioAgent, named Aubrai, was launched in August 2025 in collaboration with VitaDAO and longevity researcher Dr. Aubrey de Grey. During its initial operational phase, Aubrai successfully raised over $900,000 in research funding and generated more than a thousand hypotheses that were recorded onchain.
How BIO on BNB Chain Fits Into DeSci Expansion
The introduction of trading access on BNB Chain is a strategic component of Bio Protocol's broader multichain initiative. The project aims to foster scientific collaboration across diverse networks by developing a consistent suite of tools applicable to multiple blockchains. The roadmap for its BNB deployment is detailed in an image shared by the Bio Protocol team.
BIO on BNB: Multichain DeSci Expansion
BNB Chain now supports several key components from the Bio ecosystem. These additions are intended to enable DeSci projects to execute their workflows natively on the BNB network.
Bio is building a full-stack solution for DeSci builders and research communities to 100X the speed of science.
— Bio Protocol (@BioProtocol) December 2, 2025
See the Bio on BNB roadmap: pic.twitter.com/n8nNjdGEtP
Components visible in the shared roadmap:
- •DeSci Bridge
The initial phase of cross-chain interoperability has been successfully completed. - •Binance Deposit and Withdrawal Support
Users can transfer BIO tokens via BNB Chain for trading or staking purposes. - •x402 BNB for BioAgent Payments
BioAgents will be equipped to receive and execute BNB-denominated tasks utilizing the x402 model, facilitating automated experimentation within BNB's cost-effective environment. - •Bridge for DeSci Projects
DeSci teams operating within the ecosystem will be able to migrate their research tools across different chains. - •DeSci Staking
Participants can support scientific endeavors by locking BIO tokens in dedicated staking pools. - •Ignition Sales on BNB
Future project launches are scheduled to take place directly on BNB Chain. - •Bio Launchpad on BNB Mainnet
This launchpad will provide support for emerging research teams seeking to introduce tokens or secure community funding for scientific experiments.
Collectively, these developments position BIO within a decentralized science network that extends across multiple blockchains. BNB users can now trade the token and engage with scientific tools without being solely reliant on Ethereum or other base networks.
How Tokenized Research Tools Fit Into DeSci
Bio Protocol develops systems that transform scientific research into verifiable, tradable, and auditable information. These tools operate through onchain contracts, offering scientists a method to coordinate global research efforts while simultaneously preventing data loss and ensuring transparent attribution.
How the system is used in practice:
- •A researcher uploads their experiments or findings into an encrypted data vault.
- •BioAgents then process this data, test related hypotheses, and issue further inquiries.
- •Onchain wallets automatically facilitate funding for subsequent laboratory testing phases.
- •Contributors receive proper attribution and token-based compensation linked to the research outcomes.
This methodology stands in contrast to traditional pharmaceutical research practices, where data is often kept confidential until patents are secured.
How BIO Supports Onchain Research Infrastructure
Within the Bio Protocol ecosystem, the BIO token is utilized for several key functions:
- •Research staking
- •Access to specific BioAgents
- •Payment for encrypted data storage
- •Coordination among scientific groups
- •Automated funding cycles
- •Attribution records associated with research outputs
The integration with BNB Chain provides the token with additional routing options and opens avenues for novel DeSci applications.
Why BNB Chain?
BNB Chain has been actively expanding its offerings for research-oriented applications. Its low transaction fees and rapid block finality are advantageous for the efficient operation of automated systems like BioAgents. Furthermore, the chain boasts a substantial user base, which contributes to enhanced liquidity for DeSci assets.
The current timing also coincides with a significant development in the broader industry. VanEck recently submitted a filing for the first spot BNB ETF in the United States. Should this application be approved, the fund would hold physical BNB and be listed on Nasdaq under the ticker VBNB. While this event is not directly related to Bio Protocol, it has the effect of increasing attention on the BNB ecosystem.
Conclusion
BIO is now available for trading on BNB Chain via PancakeSwap, offering users access to Bio Protocol's DeSci tools within a new ecosystem. This strategic move follows recent funding acquisitions and the introduction of BioAgents, which are designed to streamline onchain research coordination. With planned features including staking, bridging capabilities, launchpad support, and x402-based agent payments, the BNB integration enhances Bio Protocol's technical functionalities while ensuring a consistent research workflow across multiple blockchains.

